Symptom Guide
6 min read

What does herpes look like?

Written by Mr Stephen Lingam

Reviewed byDr Mohammad Bakhtiar(GMC: 4694470)on 25/09/2026

Key takeaways

  • Herpes usually starts with tingling or itching, then small fluid-filled blisters that break down into shallow, painful ulcers before crusting over and healing.
  • It can appear on the penis, vulva, anus, mouth or lips, because both HSV-1 and HSV-2 can infect any of these sites.
  • A first episode is often the most painful and can come with flu-like symptoms; repeat outbreaks are usually milder and shorter.
  • Syphilis sores, genital warts, folliculitis, thrush and ingrown hairs can all be mistaken for herpes, which is why a clinical look matters more than a photo comparison.
  • A swab taken from an open sore is the most reliable way to confirm herpes, and at Sexual Health Clinic London the PCR swab costs £120.63 (the blood test is £103.75), with results in 2 to 3 days.
  • Blood tests look for antibodies rather than the virus itself, so they cannot say which site is infected or when the infection happened.

Herpes looks different at each stage: first a patch of tingling or itchy skin, then a cluster of small blisters, then shallow ulcers, then a crust as it heals. It can appear on the genitals, anus, mouth or lips. If you have a sore now, the clearest next step is a herpes test while it is still visible.

Next step

Book a herpes test

Consultation, examination, testing and treatment at our Harley Street clinic. Most results within 24 hours.

Herpes is one of the most common causes of genital sores, and it is often confused with other conditions until it is examined properly. Our guide to private STI testing in London explains how a confidential visit works.

What are the first signs of herpes?

The first sign is often tingling, itching or a burning feeling on the skin, sometimes a day or two before anything is visible. This is caused by the virus travelling along the nerve to the skin surface. Some people also feel generally unwell, with aching or swollen glands in the groin, before any mark appears. This early stage is easy to dismiss as irritation, which is why the next stage, when small blisters form, is usually what prompts people to look more closely.

What do the blisters and sores actually look like?

The blisters are small, fluid-filled and usually appear in a cluster rather than as a single spot. They sit on a reddened base of skin and can be on the shaft or head of the penis, the vulva, the anus, the mouth or the lips. Within a day or two the blisters break open, leaving shallow, often painful ulcers. These can weep or sting, particularly when urine passes over them, before drying out and forming a crust as the skin heals underneath. The whole cycle, from first blister to healed skin, can take up to 3 to 4 weeks for a first episode.

Does a first outbreak look different from a repeat one?

Yes, a first episode is usually more extensive and more uncomfortable than any outbreak that follows. Along with the sores, a first episode can bring flu-like symptoms: fever, headache, muscle aches and tender, swollen lymph nodes in the groin. Recurrences tend to involve fewer blisters, in roughly the same area, that heal faster and with milder discomfort. Many people also notice the same tingling warning sign before each recurrence, which can prompt them to start treatment early if a doctor has prescribed it in advance.

Does herpes look the same on the penis, vulva, anus and mouth?

The pattern of tingling, blistering, ulceration and crusting is the same wherever it occurs, but the appearance is shaped by the skin at that site. On the penis, blisters and ulcers typically appear on the shaft, glans or foreskin. On the vulva, they can affect the labia and the area around the vaginal opening, and swelling can make the whole area feel sore rather than showing a single clear lesion. Around the anus, sores can be mistaken for a fissure or piles. On the mouth and lips, herpes usually shows as a cold sore, a cluster of small blisters at the edge of the lip that crusts over within a few days.

What else can look like herpes?

Several other conditions can produce marks or sores in the same area, which is exactly why a clinical examination and the right test matter more than trying to match a description online.

A short summary of what tends to be confused with herpes, and how it is told apart.

Herpes
What it looks like
Clustered blisters, then shallow ulcers, then a crust
Pain
Often painful, tingling beforehand
Test
Swab of the sore, or a blood test
Syphilis (primary stage)
What it looks like
A single, firm, round sore (chancre)
Pain
Usually painless
Genital warts
What it looks like
Small, flesh-coloured, sometimes cauliflower-shaped growths
Pain
Usually painless
Folliculitis
What it looks like
Small red or white-topped spots around hair follicles
Pain
Mild tenderness
Test
Clinical examination
Thrush-related fissures
What it looks like
Redness with a thin, cracked skin split, often with white residue
Pain
Stinging, especially urinating
Test
Swab
Ingrown hairs
What it looks like
A single raised, sometimes pus-filled bump near a hair
Pain
Mild tenderness
Test
Clinical examination

Genital warts and molluscum tend to be painless bumps rather than blisters or ulcers, folliculitis and ingrown hairs sit around hair follicles rather than forming a cluster of blisters, and thrush more often causes redness, itching and a white discharge than a defined sore. Because these can overlap in appearance, especially in early or mild cases, the reliable route is an examination rather than comparing photographs. A doctor who has seen many of these presentations can usually tell them apart on sight and confirm with the right test. Our herpes myths and facts page covers more of the common misconceptions people bring to this question.

How is herpes actually tested and confirmed?

The most accurate way to confirm herpes is a swab taken directly from an open sore or blister while it is still present, because this tests for the virus itself. A blood test looks for antibodies your immune system has made in response to past infection, which means it can show that you have been exposed to HSV-1 or HSV-2 at some point, but it cannot tell you where the infection is, when you caught it, or whether a specific sore in front of you is herpes. If you want a blood test after a possible exposure rather than because of a visible sore, it is generally more reliable from around 12 weeks after that exposure, once antibodies have had time to develop.

How testing works at our Harley Street clinic

At Sexual Health Clinic London, the herpes swab is best taken as soon as possible after a sore appears, ideally while it is still fluid-filled rather than after it has crusted over, because this is when the sample contains the most virus. The blood antibody test needs no specific preparation. Both tests are available with a walk-in appointment seven days a week at 117a Harley Street, and results are back in 2 to 3 days. If you are being screened more broadly rather than testing one symptom, the Silver package includes HSV I and II alongside chlamydia, gonorrhoea, HIV, syphilis, Mycoplasma genitalium, Ureaplasma and Gardnerella.

Book a herpes test at 117a Harley Street: PCR swab £120.63 or blood test £103.75, results in 2 to 3 days.

References

  • Genital herpes, NHS
  • Genital herpes, NICE Clinical Knowledge Summaries
  • UK national guideline for the management of genital herpes, British Association for Sexual Health and HIV (BASHH)
  • Syphilis, NHS
  • Genital warts, NHS

For confidential testing and treatment, visit our our Harley Street clinic in London. Same-day appointments and walk-ins available.

Next step

Book a herpes test

Consultation, examination, testing and treatment at our Harley Street clinic. Most results within 24 hours.

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Frequently Asked Questions

Book a herpes test

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Mon-Fri 9am-6pm, Sat-Sun 10am-2pm. Walk-ins welcome.